The main rule on using propolis for the first time, be it for internal or external use is to start with smaller doses to be gradually increased. The reason for it is that you may be one of those rare persons who may have some allergy to it, namely dermatitis. If reddening of the skin occurs, all that has to be done is stopping the treatment.
For external use on cuts, wounds, burns, allergies like eczema, on areas with fungi like athlete's foot, ring worm or candida manifestations, mosquito bites, herpes or acne, to dilute a couple of drops of the tincture in a tea spoon of warm water (1 to 6) and spread to the infected areas should do the trick.
On serious acne, herpes and candida internal use is also recommended. At bedtime small amounts should be placed on top of acne cysts to dry them out. A few drops of propolis in a good gel or cream plus a bit of honey, will make an excellent ointment/moisturiser, sun radiation shield and skin repairer from previous damage.
For internal use one should start with two or three drops twice a day. This amount can be increased to fifteen drops or higher. In this case it would be for cancer or HIV treatment. It can be dilute in honey or water. Five to eight drops twice a day should be the average daily dose for acquiring and maintaining a good immune system.
As propolis stops virus from propagating by not allowing them to come out of their protective protein coating, to prevent colds and flu's the normal daily dose should be more than enough. It will also double the normal antibiotics efficiency when taken together.
For mouth hygiene, including mouth sores, receding gums, plaque and teeth caries, after normal dental cleaning one could brush with a couple of drops, gargle and swallow.
These are adult doses. Children's should be roughly half.